Ryanodine receptor 1 signaling in dendritic cells
نویسندگان
چکیده
منابع مشابه
Ca2+ signaling through ryanodine receptor 1 enhances maturation and activation of human dendritic cells.
Increases in intracellular Ca2+ concentration accompany many physiological events, including maturation of dendritic cells, professional antigen-presenting cells characterized by their ability to migrate to secondary lymphoid organs where they initiate primary immune responses. The mechanism and molecules involved in the early steps of Ca2+ release in dendritic cells have not yet been defined. ...
متن کاملErratum Ca2+ signaling through ryanodine receptor 1 enhances maturation and activation of human dendritic cells
Laura Bracci1,*,‡, Mirko Vukcevic2,*, Giulio Spagnoli1, Sylvie Ducreux2, Francesco Zorzato3 and Susan Treves2,3,§ 1Institute of Surgical Research and 2Departments of Anesthesia and Research, Basel University Hospital, Hebelstrasse 20, 4031 Basel, Switzerland 3Department of Experimental and Diagnostic Medicine, General Pathology Section, University of Ferrara, 44100 Ferrara, Italy *These authors...
متن کاملCalcineurin upregulates local Ca signaling through ryanodine receptor-1 in airway smooth muscle cells
Carlo P. Savoia, Qing-Hua Liu, Yun-Min Zheng, Vishal Yadav, Zhen Zhang, Ling-Gang Wu, and Yong-Xiao Wang Center for Cardiovascular Sciences, Albany Medical College, Albany, New York; Institute for Medical Biology, College of Life Sciences, South-Central University for Nationalities, Wuhan, Hubei, China; Synaptic Transmission Section, National Institute of Neurological Disorders and Stroke, Beth...
متن کاملCalcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.
Local Ca(2+) signals (Ca(2+) sparks) play an important role in multiple cellular functions in airway smooth muscle cells (ASMCs). Protein kinase Cϵ is known to downregulate ASMC Ca(2+) sparks and contraction; however, no complementary phosphatase has been shown to produce opposite effects. Here, we for the first time report that treatment with a specific calcineurin (CaN) autoinhibitory peptide...
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Dendritic cells (DCs) are a heterogeneous family of professional APCs involved in priming adaptive immune responses. Donor DCs (direct pathway of allorecognition) and recipient DCs presenting processed donor major histocompatibility complex (MHC) as peptides (indirect pathway of allorecognition) participate actively in graft rejection by stimulating recipient T cell responses following organ tr...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2008.12.539